Keto Versus Mediterranean Food plan: Which Is Finest for T2 Diabetics and Prediabetics?

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Impact of a Ketogenic Food plan versus a Mediterranean Food plan on HbA1c in People with Prediabetes and Sort 2 Diabetes Mellitus: the Interventional Keto-Med Randomized Crossover Trial

Proper off the bat, I do not like that they studied each diabetes and prediabetics. There have been solely 40 unique research contributors, with full information on solely 33. Why lump the 2 collectively?

Individuals adopted every food regimen for 12 weeks then lab information and physique weight have been assessed.

The researchers conclusions:

HbA1c [a measure of blood sugar control] was not completely different between food regimen phases after 12-weeks, however improved from baseline on each diets, probably as a result of a number of shared dietary features. WFKD [ketogenic diet] was helpful for larger lower in triglycerides, but in addition had potential untoward dangers from elevated LDL-C, and decrease nutrient intakes from avoiding legumes, fruits, and entire intact grains, in addition to being much less sustainable.

Triglycerides dropped extra on the keto food regimen, no shock. Physique weight dropped the identical for each diets, 7-8%. HDL-cholesterol (the “good ldl cholesterol”) rose 11% on keto and seven% on the Mediterranean food regimen. HgbA1c dropped the identical on each diets, about 8% from baseline. Each diets result in consuming ~300 energy much less per day than baseline consumption.

Dr Bret Scher addressed the elevated LDL-cholesterol (aka “unhealthy ldl cholesterol”) over at

The authors reported that LDL “dangerously” rose 10% on the keto food regimen. However was it actually a harmful change? Triglycerides went down on the keto food regimen, as we might anticipate. And as we noticed in 2018 with the Virta Well being trial, on common, LDL went up 10%. Nonetheless, the calculated cardiac danger rating went down 12%.

By way of answering the headline query, Keto Versus Mediterranean Food plan: Which Is Finest for T2 Diabetics and Prediabetics?, the reply actually will depend on long-term information regarding longevity and varied illnesses. This research would not reply the query.

What say you?

Steve Parker, MD

front cover of Conquer Diabetes and Prediabetes